陈庆安 (Qing-An Chen)-手性合成研究组

陈庆安 (Qing-An Chen)

陈庆安（Qing An-Chen）

Ph.D. (2007-2012)

Dalian Institute of Chemical Physics,
Chinese Academy of Sciences,
457 Zhongshan Road, Dalian 116023, P. R. China

Tel: 86-411-84379325(office)
E-mail: chenan@mail.ustc.edu.cn
URL:http://www.researcherid.com/rid/F-7463-2011

Educational and Professional Background：

2008.9-2012.7, Ph.D. in Organic Chemistry, Advisor Prof. Yong-Gui Zhou, Dalian Insititute of Chemical Physics, CAS.
2007.9-2008.7, Graduate Course, University of Science and Technology of China.
2003.9-2007.7, B.S. in Chemistry, University of Science and Technology of China.

Awards：

First Prize of Natural Science of Liaoning Province, 2016.
Excellent President Award of Chinese Academy of Science for Graduates, 2012.
The First Prize Scholarship of Yan Chang Petroleum, 2011.
The Zhuliyuehua Scholarship for Excellent Doctoral Student of Chinese Academy of Sciences, 2011.
Merit Student of Chinese Academy of Sciences, 2010.

Representative Publications:

21. Mu-Wang Chen, Yue Ji, Jie Wang, Qing-An Chen, Lei Shi and Yong-Gui Zhou.* Asymmetric Hydrogenation of Isoquinolines and Pyridines Using Hydrogen Halide Generated in situ as Activator. Org. Lett. 2017, 19, 4988-4991.

20. Hong-Qiang Liu, Lei Shi, Qing-An Chen, Lei Wang* and Yong-Gui Zhou.* Synthesis of MeO-PEG-Supported Ferrocenyloxazoline Ligands and Their Application in Asymmetric Catalysis. Acta Chim. Sinica 2013, 71, 40-43.

19. Qing-An Chen, Zhi-Shi Ye, Ying Duan and Yong-Gui Zhou.* Homogeneous Palladium-catalyzed Asymmetric Hydroge-nation. Chem. Soc. Rev. 2013, 42, 497-511.

18. Zhi-Shi Ye, Mu-Wang Chen,Qing-An Chen, Lei Shi, Ying Duan and Yong-Gui Zhou.* Ir-Catalyzed Asymmetric Hydrogenation of Pyridinium Salts. Angew. Chem. Int. Ed. 2012, 51, 10181-10184.
<Highlighted by Angew. Chem. Int. Ed. 2013, 52, 9616>

17. Kai Gao, Bo Wu, Chang-Bin Yu, Qing-An Chen, Zhi-Shi Ye and Yong-Gui Zhou.* Iridium Catalyzed Asymmetric Hydrogenation of Cyclic Imines of Benzodiazepinones and Benzodiazepines. Org. Lett. 2012, 14, 3890–3893.
<Highlighted by Synfacts 2012, 1227 >

16. Chang-Bin Yu, Kai Gao, Qing-An Chen, Mu-Wang Chen and Yong-Gui Zhou.* Enantioselective Pd-Catalyzed Hydroge- nation of Tetrasubstituted Olefins of Cyclic β-(Arylsulfonamido)acrylates. Tetrahedron Lett. 2012, 53, 2560-2563.

15.Qing-An Chen, Kai Gao, Ying Duan, Zhi-Shi Ye, Lei Shi, Yan Yang and Yong-Gui Zhou.* Dihydrophenanthridine: A New and Easily Regenerable NAD(P)H Model for Biomimetic Asymmetric Hydrogenation. J. Am. Chem. Soc. 2012, 134, 2442-2448.
<Highlighted by Synlett 2012, 1300 >
<Highlighted by Angew Chem. Int. Ed. 2012, 51, 11423-11425 >

14. Mu-Wang Chen, Qing-An Chen, Ying Duan, Zhi-Shi Ye and Yong-Gui Zhou. * Asymmetric Hydrogenolysis of Racemic Tertiary Alcohol, 3-Substituted 3-Hydroxyisoindolin-1-ones. Chem. Commun. 2012, 48, 1698-1700.

13. Ying Duan, Mu-Wang Chen, Qing-An Chen, Chang-Bin Yu and Yong-Gui Zhou.* Pd-Catalyzed Asymmetric Hydrogenation of 3-(Toluenesulfonamidoalkyl)indoles. Org. Biomol. Chem. 2012, 10, 1235-1238.

12. Duo-Sheng Wang, Qing-An Chen, Sheng-Mei Lu and Yong-Gui Zhou.* Asymmetric Hydrogenation of Heteroarenes and Arenes. Chem.Rev. 2012, 112, 2557-2590.

11. Qing-An Chen, Mu-Wang Chen, Chang-Bin Yu, Lei Shi, Duo-Sheng Wang, Yan Yang and Yong-Gui Zhou.* Biomimetic Asymmetric Hydrogenation: In Situ Regenerable Hantzsch Esters for Asymmetric Hydrogenation of Benzoxazinones. J. Am. Chem. Soc. 2011, 133, 16432-16435.
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10. Duo-Sheng Wang, Zhi-Shi Ye, Qing-An Chen, Yong-Gui Zhou,* Chang-Bin Yu, Hong-Jun Fan,* and Ying Duan. Highly Enantioselective Partial Hydrogenation of Simple Pyrroles:A Facile Access to Chiral 1-Pyrrolines. J. Am. Chem. Soc. 2011, 133, 8866-8869.

9. Ying Duan, Mu-Wang Chen, Zhi-Shi Ye, Duo-Sheng Wang, Qing-An Chen, and Yong-Gui Zhou.* An Enantioselective Approach to 2,3-Disubstituted Indolines through Consecutive Bronsted Acid/Pd-Complex-Promoted Tandem Reactions. Chem. Eur. J. 2011, 17, 7193-7197.

8. Qing-An Chen, Duo-Sheng Wang, Yong-Gui Zhou,* Ying Duan, Hong-Jun Fan,* Yan Yang, and Zhang Zhang. Convergent Asymmetric Disproportionation Reactions: Metal/Bronsted Acid Relay Catalysis for Enantioselective Reduction of Quinoxalines. J. Am. Chem. Soc. 2011, 133, 6126-6129.
<Highlighted by SYNFACTS 2011, 673 >

7. Mu-Wang Chen, Ying Duan, Qing-An Chen, Duo-Sheng Wang, Chang-Bin Yu, and Yong-Gui Zhou.* Enantioselective Pd-Catalyzed Facile Access to Chiral Fluorinated Amines. Org. Lett. 2010, 12, 5075-5077.
<Highlighted by SYNFACTS 2011, 188>

6. Duo-Sheng Wang, Qing-An Chen, Wei Li, Chang-Bin Yu, Yong-Gui Zhou,* and Xumu Zhang.* Pd-Catalyzed Asymmetric Hydrogenation of Unprotected Indoles Activated by Bronsted Acids. J.Am. Chem. Soc. 2010, 132, 8909-8911.
<Highlighted by SYNFACTS 2010, 1039>

5. Qing-An Chen, Duo-Sheng Wang and Yong-Gui Zhou.* Bifunctional AgOAc-catalyzed Asymmetric Reactions. Chem. Commun., 2010, 46, 4043-4051(Feature Article).

4. Qing-An Chen, Xiang Dong, Mu-Wang Chen, Duo-Sheng Wang, Yong-Gui Zhou,* and Yu-Xue Li.* Highly Effective and Diastereoselective Synthesis of Axially Chiral Bis-sulfoxide Ligands via Oxidative Aryl Coupling. Org. Lett. 2010, 12, 1928-1931.
<Highlighted by SYNFACTS 2010, 897.>

3. Da-Wei Wang, Duo-Sheng Wang, Qing-An Chen, Yong-Gui Zhou* Asymmetric Hydrogenation with Water/Silane as the Hydrogen Source. Chem. Eur. J. 2010, 16, 1133-1136.

2. Qing-An Chen, Wei Zeng, Yong-Gui Zhou.* AgOAc-catalyzed Asymmetric Amination of Glycine Schiff Bases with Azodicarboxylates. Tetrahedron Lett. 2009, 50, 6866-6868.

1. Qing-An Chen, Wei Zeng, Da-Wei Wang, Yong-Gui Zhou.* Bifunctional Silver Acetate Catalyzed Asymmetric Mannich-Type Reactions. Synlett. 2009, 2236-2241.

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