余长斌 (Chang-Bin Yu)

余长斌(Chang-Bin Yu)

Associate Professor

Dalian Institute of Chemical Physics, 
Chinese Academy of Sciences, 
457 Zhongshan Road, Dalian 116023, P. R. China

Tel: 86-411-84379325 (office)
E-mail: cbyu@dicp.ac.cn

URL: http://www.researcherid.com/rid/C-8963-2012


Educational and Professional Background:

2009.9-2012.5, Ph. D. in Organic Chemistry, Advisor Prof. Yong-Gui Zhou, Dalian Institute of Chemical Physics, CAS. 

2005.7- present, Assistant Research Fellow, Dalian Institute of Chemical Physics, Chinese Academy of Sciences (DICP), China.

2002.9-2005.7, M.S. in Inorganic chemistry, advisor Prof. Rui-Xiang Li, Sichuan University, China.



Representative Publications:

30. Chang-Bin Yu, Jie Wang and Yong-Gui Zhou.* Facile Synthesis of Chiral Indolines through  Asymmetric Hydrogenation of in situ Generated  Indoles. Org. Chem. Front. 2018, 5, 2805-2809.



29. Bo Song, Yue Ji, Shu-Bo Hu, Chang-Bin Yu and Yong-Gui Zhou.*  Synthesis of Chiral γ-Sultams through Intramolecular Reductive Amination with Sulfonylcarbamate as N-source. Tetrahedron Lett. 2017, 58, 1528-1530.


28. Bo Song, Chang-Bin Yu,  Yue Ji, Mu-Wang Chen and Yong-Gui Zhou.* Synthesis of Chiral Sultams via Palladium-catalyzed Intramolecular Asymmetric Reductive Amination. Chem. Commun. 2017, 53, 1704-1707.


27. Wen-Xue Huang, Chang-Bin Yu, Yue Ji, Lian-Jin Liu  and Yong-Gui Zhou.* Ir-Catalyzed Asymmetric Hydrogenation of Heteroaromatics Bearing a Hydroxyl Group, 3-Hydroxypyridinium Salts. ACS Catal. 2016, 6, 2368-2371.


26.  Zhang-Pei             Chen,                                      Mu-Wang             Chen,                                      Lei             Shi, Chang-Bin             Yu and Yong-Gui Zhou.* Pd-catalyzed Asymmetric Hydrogenation of Fluorinated Aromatic Pyrazol-5-ols via Capture of Active Tautomers. Chem. Sci. 2015, 6, 3415-3419.


25. Bo Song, Chang-Bin Yu, Wen-Xue Huang, Mu-Wang Chen,  and Yong-Gui Zhou.* Formal Palladium-Catalyzed Asymmetric Hydrogenolysis of Racemic N-Sulfonyloxaziridines. Org. Lett. 2015, 17, 190-193.


24. Chang-Bin Yu,                            Wen-Xue Huang, Lei Shi, Mu-Wang Chen, Bo Wu, and Yong-Gui Zhou.* Asymmetric Hydrogenation via Capture of Active Intermediates Generated from Aza-Pinacol Rearrangement. J. Am. Chem. Soc. 2014, 136, 15837-15840.


23.     Wen-Xue Huang, Chang-Bin Yu, Lei Shi and Yong-Gui Zhou.* Iridium-Catalyzed Asymmetric Hydrogenation of Pyrrolo[1,2-a]pyrazinium Salts. Org. Lett. 2014, 16, 3324-3327.


22.   Ying Duan,                                                            Lu Li,                              Mu-Wang Chen,                              Chang-Bin Yu,                              Hong-Jun Fan*                              and Yong-Gui  Zhou.* Homogenous Pd-Catalyzed Asymmetric Hydrogenation of Unprotected Indoles: Scope and Mechanistic Studies. J. Am. Chem. Soc. 2014, 136, 7688-7700.


21.  Bo Wu, Mu-Wang Chen, Zhi-Shi Ye, Chang-Bin Yu and Yong-Gui Zhou.* A Streamlined Synthesis of 2,3-Dihydrobenzofurans via the ortho-Quinone Methides Generated from 2-Alkyl-Substituted Phenols. Adv. Synth. Catal. 2014, 356, 383-387.


20. Chang-Bin Yu, Yong-Gui Zhou*. Palladium-Catalyzed Asymmetric Hydrogenolysis of N-Sulfonyl                              Aminoalcohols via Achiral Enesulfonamide Intermediates. Angew. Chem. Int. Ed. 2013, 52, 13365-13368.

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19. Kai Gao, Bo Wu, Chang-Bin Yu, Qing-An Chen, Zhi-Shi Ye and Yong-Gui Zhou.* Iridium Catalyzed Asymmetric Hydrogenation of Cyclic Imines of Benzodiazepinones and Benzodiazepines. Org. Lett. 2012, 14, 3890–3893.
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18. Chang-Bin Yu, Kai Gao, Qing-An Chen, Mu-Wang Chen and Yong-Gui Zhou.* Enantioselective Pd-Catalyzed Hydrogenation of Tetrasubstituted Olefins of Cyclic β-(Arylsulfonamido)acrylates. Tetrahedron Lett. 2012, 53, 2560-2563.


17. De-Yang Zhang, Chang-Bin Yu, Min-Can Wang,* Kai Gao and Yong-Gui Zhou.* A New Electronically Deficient Atropisomeric Diphosphine Ligand (S)-CF3OBiPhep and Its Application in Asymmetric Hydrogenation. Tetrahedron Lett. 2012, 53, 2556-2559.



16. Kai Gao, Chang-Bin Yu, Duo-Sheng Wang and Yong-Gui Zhou.* Iridium-Catalyzed Asymmetric Hydrogenation of 3-Substituted 2H-1,4-Benzoxazines. Adv. Synth. Catal. 2012, 354, 483-488.



15. Ying Duan, Mu-Wang Chen, Qing-An Chen, Chang-Bin Yu  and Yong-Gui Zhou.*   Pd-Catalyzed Asymmetric Hydrogenation of 3-(Toluenesulfonamidoalkyl)indoles. Org.                                Biomol. Chem. 2012, 10, 1235-1238.



14. Qing-An Chen, Mu-Wang Chen, Chang-Bin Yu, Lei Shi, Duo-Sheng Wang, Yan  Yang and Yong-Gui Zhou.*   Biomimetic Asymmetric Hydrogenation: In Situ Regenerable Hantzsch Esters  for Asymmetric Hydrogenation of Benzoxazinones. J.                              Am. Chem. Soc. 2011, 133, 16432-16435.
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13. De-Yang Zhang, Duo-Sheng Wang, Min-Can Wang,* Chang-Bin Yu, Kai Gao and Yong-Gui Zhou.* Synthesis of Electronically Deficient Atropisomeric Bisphosphine Ligands and Their Application in Asymmetric Hydrogenation of Quinolines. Synthesis. 2011, 2796-2802.



12. Kai Gao, Chang-Bin Yu, Wei Li, Yong-Gui Zhou* and Xumu Zhang.* Synthesis and Enantioselective Hydrogenation of Seven-membered Cyclic  Imines: Substituted Dibenzo[b,f][1,4]oxazepines. Chem. Commun. 2011, 7845-7847.



11. Duo-Sheng Wang, Zhi-Shi Ye, Qing-An Chen, Yong-Gui Zhou,* Chang-Bin Yu,                              Hong-Jun Fan,* and Ying Duan.  Highly Enantioselective Partial Hydrogenation of Simple Pyrroles:                              A Facile Access to Chiral 1-Pyrrolines. J.                                Am. Chem. Soc. 2011, 133, 8866-8869.



10. Chang-Bin Yu, Kao Gao, Duo-Sheng Wang, Lei Shi and Yong-Gui Zhou.*  Enantioselective Pd-catalyzed Hydrogenation of  Enesulfonamides. Chem. Commun. 2011, 47,5052-5054.
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9. Duo-Sheng Wang, Jie Tang, Yong-Gui Zhou,* Mu-Wang Chen, Chang-Bin Yu, Ying Duan                              and Guo-Fang Jiang.* Dehydration Triggered Asymmetric Hydrogenation of 3-(a-hydroxyalkyl)indoles. Chem. Sci. 2011, 2, 803-806.
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8. Mu-Wang Chen, Ying Duan, Qing-An Chen, Duo-Sheng Wang, Chang-Bin Yu, and Yong-Gui Zhou.* Enantioselective Pd-Catalyzed                              Hydrogenation of Fluorinated Imines:                              Facile Access to Chiral Fluorinated Amines. Org. Lett. 2010, 12, 5075-5077.
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7. Duo-Sheng Wang, Qing-An Chen, Wei Li, Chang-Bin Yu, Yong-Gui Zhou,* and Xumu Zhang.*                              Pd-Catalyzed Asymmetric Hydrogenation of Unprotected Indoles Activated by                              Bronsted Acids. J.                                Am. Chem. Soc. 2010, 132, 8909-8911.
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6. Ben-Hu Zhu, Jun-Cheng Zheng, Chang-Bin Yu, Xiu-Li Sun, Yong-Gui Zhou, Qi Shen* and Yong Tang.* One-Pot Highly Diastereoselective Synthesis of cis-Vinylaziridines via the Sulfur Ylide-Mediated Aziridination and Palladium(0)-Catalyzed Isomerization. Org. Lett. 2010, 12, 504.



5. Chang-Bin Yu, Da-Wei Wang, Yong-Gui Zhou.* Highly Enantioselective Synthesis of Sultams via Pd-Catalyzed Hydrogenation. J. Org. Chem. 2009, 74, 5633-5635.



4. Xiao-Bing Wang, Da-Wei Wang, Sheng-Mei Lu, Chang-Bin Yu, Yong-Gui Zhou.* Highly Enantioselective Ir-catalyzed Hydrogenation of Exocyclic Enamines.Tetrahedron: Asymmetry 2009, 20, 1040-1045.



3. Da-Wei Wang, Xiao-Bing Wang, Duo-Sheng Wang,  Sheng-Mei Lu, Chang-Bin Yu, Yong-Gui Zhou.* Highly Enantioselective Iridium-Catalyzed Hydrogenation of 2-Benzylquinolines, 2-Functionalized and 2,3-Disubstituted Quinolines. J. Org. Chem. 2009, 74, 2780-2787.
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2. You-Qing Wang, Chang-Bin Yu, Da-Wei Wang, Xiao-Bing Wang, Yong-Gui Zhou.* Enantioselective Synthesis of Cyclic Sulfamidates via Pd Catalyzed Hydrogenation. Org. Lett. 2008, 10, 2071-2074.
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1. Qi-Bin Liu, Chang-Bin Yu, Yong-Gui Zhou.* Synthesis of Tunable Phosphinite-pyridine Ligands and Their Application in Asymmetric Hydrogenation. Tetrahedron Lett. 2006, 47, 4733-4736.