陈木旺(Mu-Wang Chen)

Assistant Research Fellow

Dalian Institute of Chemical Physics,
Chinese Academy of Sciences,
457 Zhongshan Road, Dalian 116023, P. R. China

Tel: 86-411-84379325 (office)
E-mail: chemmuwang@dicp.ac.cn

URL: http://www.researcherid.com/rid/A-9324-2015

 

Educational Background

2009.7- present, Assistant Research Fellow, Dalian Institute of Chemical Physics, Chinese Academy of Sciences (DICP), China.

2006.9-2009.7, M.S. in Chemistry, University of Wenzhou

 
Awards:
 
 
Representative Publications:
 
34. Bo Song, Chang-Bin Yu, Yue Ji, Mu-Wang Chen and Yong-Gui Zhou.* Synthesis of Chiral Sultams via Palladiumcatalyzed Intramolecular Asymmetric Reductive Amination. Chem. Commun. 2017, 53, 1704-1707.



33. Mu-Wang Chen, Bo Wu, Zhang-Pei Chen, Lei Shi and Yong-Gui Zhou.* Synthesis of Chiral Fluorinated Propargylamines via Chemoselective Biomimetic Hydrogenation. Org. Lett. 2016, 18, 4650-4653.


32. Jie Wang, Mu-Wang Chen, Yue Ji, Shu-Bo Hu and Yong-Gui Zhou.* Kinetic Resolution of Axially Chiral 5- or 8-Substituted Quinolines via Asymmetric Transfer Hydrogenation. J. Am. Chem. Soc. 2016, 138, 10413-10416.


31. Zhong Yan, Bo Wu, Xiang Gao, Mu-Wang Chen and Yong-Gui Zhou.* Enantioselective Synthesis of α-Amino Phosphonates via Pd-Catalyzed Asymmetric Hydrogenation. Org. Lett. 2016, 18, 692–695.

30. Bo Wu, Xiang Gao, Zhong Yan, Mu-Wang Chen, and Yong-Gui Zhou.* C-H Oxidation/Michael Addition/Cyclization Cascade for Enantioselective Synthesis of Functionalized 2-Amino-4H-chromenes. Org. Lett. 2015, 17, 6134-6137.

29. Xiang Gao, Bo Wu, Wen-Xue Huang, Mu-Wang Chen, and Yong-Gui Zhou.* Enantioselective Palladium-Catalyzed C-H Functionalization of Indoles Using an Axially Chiral 2,2’-Bipyridine Ligand. Angew. Chem. Int. Ed. 2015, 54, 11956-11960.

28. Yue Ji, Lei Shi,* Mu-Wang Chen, Guang-Shou Feng, and Yong-Gui Zhou.* Concise Redox Deracemization of Secondary and Tertiary Amines with a Tetrahydroisoquinoline Core via a Nonenzymatic Process. J. Am. Chem. Soc. 2015, 137, 10496-10499.

27. Zhang-Pei Chen, Mu-Wang Chen, Lei Shi, Chang-Bin Yu and Yong-Gui Zhou.* Pd-catalyzed Asymmetric Hydrogenation of Fluorinated Aromatic Pyrazol-5-ols via Capture of Active Tautomers. Chem. Sci. 2015, 6, 3415-3419.

26. Mu-Wang Chen, Zhi-Shi Ye, Zhang-Pei Chen, Bo Wu and Yong-Gui Zhou.* Enantioselective synthesis of trifluoromethyl substituted piperidines with multiple stereogenic centersviahydrogenation of pyridinium hydrochlorides. Org. Chem. Front. 2015, 2, 586-589.

25. Wen-Xue Huang, Bo Wu, Xiang Gao, Mu-Wang Chen, Baomin Wang,* and Yong-Gui Zhou.* Iridium-Catalyzed Selective Hydrogenation of 3-Hydroxypyridinium Salts: A Facile Synthesis of Piperidin-3-ones. Org. Lett. 2015, 17, 1640-1643.

24. Bo Wu, Xiang Gao, Mu-Wang Chen and Yong-Gui Zhou.* Direct amination of 2-(1-tosylalkyl) phenols with aqueous ammonia: a metal-free synthesis of primary amines.Tetrahedron Lett. 2015, 56, 1135–1137.

23. Yue Ji, Mu-Wang Chen, Lei Shi* and Yong-Gui Zhou.* Highly selective partial dehydrogenation of tetrahydroisoquinolines using modified Pd/C. Chin. J. Catal. 2015, 36, 33-39.

22. Bo Song, Chang-Bin Yu, Wen-Xue Huang, Mu-Wang Chen, and Yong-Gui Zhou.* Formal Palladium-Catalyzed Asymmetric Hydrogenolysis of Racemic N-Sulfonyloxaziridines. Org. Lett. 2015, 17, 190-193.

21. Chang-Bin Yu, Wen-Xue Huang, Lei Shi, Mu-Wang Chen, Bo Wu, and Yong-Gui Zhou.* Asymmetric Hydrogenation via Capture of Active Intermediates Generated from Aza-Pinacol Rearrangement. J. Am. Chem. Soc. 2014, 136, 15837-15840.

20. Bo Wu, Xiang Gao, Mu-Wang Chen, and Yong-Gui Zhou.* A Concise Synthesis of 2-(2-Hydroxy-phenyl)acetonitriles via the o-Quinone Methides Generated from 2-(1-Tosylalkyl)phenols. Chin. J. Chem. 2014, 32, 981-984.

< Cover Article 2014, 32, 10 >

19. Mu-Wang Chen, Xian-Feng Cai, Zhang-Pei Chen, Lei Shi and Yong-Gui Zhou.* Facile construction of three contiguous stereogenic centers via dynamic kinetic resolution in asymmetric transfer hydrogenation of quinolines. Chem. Commun. 2014, 50, 12526-12529.

18. Ying Duan, Lu Li, Mu-Wang Chen, Chang-Bin Yu, Hong-Jun Fan* and Yong-Gui Zhou.* Homogenous Pd-Catalyzed Asymmetric Hydrogenation of Unprotected Indoles: Scope and Mechanistic Studies. J. Am. Chem. Soc. 2014, 136, 7688-7700.

     
17. Jing Luo, Bo Wu, Mu-Wang Chen, Guo-Fang Jiang* and Yong-Gui Zhou.* The Concise Synthesis of Spiro-Cyclopropane Compounds via the Dearomatization of Indole Derivatives. Org. Lett. 2014, 16, 2578-2581.

     
16. Xian-Feng Cai, Ran-Ning Guo, Mu-Wang Chen, Lei Shi and Yong-Gui Zhou.* Synthesis of Chiral Exocyclic Amines via Asymmetric Hydrogenation of Aromatic Quinolin-3-amines. Chem. Eur. J. 2014, 20, 7245-7248.

     
15. Zhang-Pei Chen, Mu-Wang Chen, Ran-Ning Guo and Yong-Gui Zhou.* 4,5-Dihydropyrrolo[1,2-a] quinoxalines: A Tunable and Regenerable Biomimetic Hydrogen Source. Org. Lett. 2014, 16, 1406–1409.

     
14. Bo Wu, Mu-Wang Chen, Zhi-Shi Ye, Chang-Bin Yu and Yong-Gui Zhou.* A Streamlined Synthesis of 2,3-Dihydrobenzofurans via the ortho-Quinone Methides Generated from 2-Alkyl-Substituted Phenols. Adv. Synth. Catal. 2014, 356, 383-387.

     
13. Zhang-Pei Chen, Zhi-Shi Ye, Mu-Wang Chen and Yong-Gui Zhou*. Enantioselective Synthesis of Endo-Cyclic Beta-Amino Acids with Two Contiguous Stereocenters via Hydrogenation of 3-Carbalkoxy-2-Substituted Quinolines. Synthesis 2013, 3239-3244.

12. Ran-Ning Guo, Xian-Feng Cai, Lei Shi, Zhi-Shi Ye, Mu-Wang Chen and Yong-Gui Zhou.* An Efficient Route to Chiral N-Heterocycles Bearing C-F Stereogenic Center via Asymmetric Hydrogenation of Fluorinated Isoquinolines. Chem. Commun. 2013, 49, 8537-8539.

11. Xian-Feng Cai, Mu-Wang Chen, Zhi-Shi Ye, Ran-Ning Guo, Lei Shi, Yan-Qin Li and Yong-Gui Zhou.* Asymmetric Transfer Hydrogenation of Aromatic Nitro Compounds, 3-Nitroquinolines: A Facile Access to Cyclic Nitro Compounds with Two Contiguous Stereocenters. Chem. Asian J. 2013, 8, 1381-1385.

10. Zhi-Shi Ye, Ran-Ning Guo, Xian-Feng Cai, Mu-Wang Chen, Lei Shi and Yong-Gui Zhou.* Enantioselective Iridium-Catalyzed Hydrogenation of 1- and 3-Substituted Isoquinolinium Salts. Angew. Chem. Int. Ed. 2013 , 52, 3685-3689.

<Highlighted by Angew. Chem. Int. Ed. 2013, 52, 9616 >

 

9. Mu-Wang Chen, Liang-Liang Cao, Zhi-Shi Ye, Guo-Fang Jiang and Yong-Gui Zhou.* A Mild Method for Generation of o-Quinone Methide under the Basic Condition. The Facile Synthesis of trans-2,3-Dihydrobenzofurans. Chem. Commun. 2013, 49, 1660-1662.

8. Zhi-Shi Ye, Mu-Wang Chen, Qing-An Chen, Lei Shi, Ying Duan and Yong-Gui Zhou.* Ir-Catalyzed Asymmetric Hydrogenation of Pyridinium Salts. Angew. Chem. Int. Ed. 2012, 51, 10181-10184.

<Highlighted by Angew. Chem. Int. Ed. 2013, 52, 9616 >

 

7. Chang-Bin Yu, Kai Gao, Qing-An Chen, Mu-Wang Chen and Yong-Gui Zhou.* Enantioselective Pd-Catalyzed Hydrogenation of Tetrasubstituted Olefins of Cyclic β-(Arylsulfonamido)acrylates. Tetrahedron Lett. 2012, 53, 2560-2563.

 

6. Mu-Wang Chen, Qing-An Chen, Ying Duan, Zhi-Shi Ye and Yong-Gui Zhou.* Asymmetric Hydrogenolysis of Racemic Tertiary Alcohol, 3-Substituted 3-Hydroxyisoindolin-1-ones. Chem. Commun. 2012, 48, 1698-1700.

 

 

5. Ying Duan, Mu-Wang Chen, Qing-An Chen, Chang-Bin Yu and Yong-Gui Zhou.* Pd-Catalyzed Asymmetric Hydrogenation of 3-(Toluenesulfonamidoalkyl)indoles. Org. Biomol. Chem. 2012, 10, 1235-1238.

 

 

4. Qing-An Chen, Mu-Wang Chen, Chang-Bin Yu, Lei Shi, Duo-Sheng Wang, Yan Yang and Yong-Gui Zhou.* Biomimetic Asymmetric Hydrogenation: In Situ Regenerable Hantzsch Esters for Asymmetric Hydrogenation of Benzoxazinones. J. Am. Chem. Soc. 2011, 133, 16432-16435.
<Highlighted by Synlett 2012, 1300 >

 

3. Ying Duan, Mu-Wang Chen, Zhi-Shi Ye, Duo-Sheng Wang, Qing-An Chen, and Yong-Gui Zhou.* An Enantioselective Approach to 2,3-Disubstituted Indolines through Consecutive Bronsted Acid/Pd-Complex-Promoted Tandem Reactions. Chem. Eur. J. 2011, 17, 7193-7197.

 

 

2. Mu-Wang Chen, Ying Duan, Qing-An Chen, Duo-Sheng Wang, Chang-Bin Yu, and Yong-Gui Zhou.* Enantioselective Pd-Catalyzed Hydrogenation of Fluorinated Imines: Facile Access to Chiral Fluorinated Amines. Org. Lett. 2010, 12, 5075-5077.
<Highlighted by SYNFACTS 2011, 188>

 

 

1. Qing-An Chen, Xiang Dong, Mu-Wang Chen, Duo-Sheng Wang, Yong-Gui Zhou,* and Yu-Xue Li.* Highly Effective and Diastereoselective Synthesis of Axially Chiral Bis-sulfoxide Ligands via Oxidative Aryl Coupling. Org. Lett. 2010, 12, 1928-1931.
<Highlighted by SYNFACTS 2010, 897.>

 

 
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