201

余长斌 研究员



余长斌(Chang-Bin Yu)

Professor


Dalian Institute of Chemical Physics,

Chinese Academy of Sciences,

457 Zhongshan Road, Dalian 116023, P. R. China

Tel: 86-411-84379325 (office)

E-mail: cbyu@dicp.ac.cn

URL:http://www.researcherid.com/rid/C-8963-2012


 

Educational and Professional Background:

2009.9-2012.5, Ph. D. in Organic Chemistry, Advisor Prof. Yong-Gui Zhou, Dalian Institute of Chemical Physics, CAS.

2002.9-2005.7, M.S. in Inorganic chemistry, Advisor Prof. Rui-Xiang Li, Sichuan University, China.



 

Awards:

 
 
Representative Publications:

2DA9

38. Yi-Xuan Ding, Zhou-Hao Zhu, Han Wang, Chang-Bin Yu* and Yong-Gui Zhou.* Construction of Three Stereocenters via Hydrogenative Desymmetrization of 2,2,5-Trisubstituted Cyclohexane-1,3-diones. Sci. China Chem. 2021, 64, 232-237.

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37. Yi-Xuan Ding, Zhou-Hao Zhu, Chang-Bin Yu* and Yong-Gui Zhou.* Recent Advances in Reductive Desymmetrization of Diketones. Asian J. Org. Chem. 2020, 9, 1942-1952.

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36. Huan-Ping Xie, Bo Wu, Mu-Wang Chen, Chang-Bin Yu, Hong-Wang Li, Xiang Li and Yong-Gui Zhou.* Enantioselective Synthesis of Triarylmethanes Bearing Pyrazole Moiety through Squaramide-catalyzed Addition of Azadienes with Pyrazolin-5-ones. Chin. J. Org. Chem. 2020, 34, 3452-3462.

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35. Han Wang, Yang Zhao, Yi-Xuan Ding, Chang-Bin Yu* andYong-Gui Zhou.* Synthesis of cis β-Hydroxy Ketones by Desymmetrization of 1,3-Cyclopentanediones through Ru-catalyzed Hydrogen Transfer. Asian. J. Org. Chem. 2020, 9, 753-756.

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34. Xiang Li, Zi-Biao Zhao, Mu-Wang Chen, Bo Wu, Chang-Bin Yu* andYong-Gui Zhou.* Palladium-catalyzed Asymmetric Hydrogenation of 2-Aryl Cyclic Ketones for the Synthesis of trans Cycloalkanols through Dynamic Kinetic Resolution under Acidic Conditions. Chem. Commun. 2020, 56, 5815-5818.

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33. Chang-Bin Yu, Heng-Ding Wang, Bo Song, Hong-Qiang Shen, Hong-Jun Fan* andYong-Gui Zhou.* Reversal of Diastereoselectivity in Palladium-Arene Interaction Directed Hydrogenative Desymmetrization of 1,3-Diketones. Sci. China Chem. 2020, 63, 215-221.

2019

32. Chang-Bin Yu, Bo Song, Mu-Wang Chen, Hong-Qiang Shen and Yong-Gui Zhou.* Construction of Multiple-Substituted Chiral Cyclohexanes through Hydrogenative Desymmetrization of 2,2,5-Trisubstituted 1,3-Cyclohexanediones. Org. Lett. 2019, 21, 9401-9404.

31. Chang-Bin Yu,* Xiang Li, Yong-Gui Zhou.* A Condensation/Reductive  Alkylation/Hydrogenation Cascade for Facile Synthesis of Chiral  2,3-Disubstituted Indolines. Asian. J. Org. Chem. 2019, 8,  1118-1121.

30. Chang-Bin Yu, Jie Wang and Yong-Gui Zhou.* Facile Synthesis of Chiral Indolines through Asymmetric Hydrogenation of in situ Generated Indoles. Org. Chem. Front. 20185, 2805-2809.

29. Bo Song, Yue Ji, Shu-Bo Hu, Chang-Bin Yu and Yong-Gui Zhou.* Synthesis of Chiral γ-Sultams through Intramolecular Reductive Amination with Sulfonylcarbamate as N-source. Tetrahedron Lett. 201758, 1528-1530.

28. Bo Song,Chang-Bin Yu, Yue Ji, Mu-Wang Chen and Yong-Gui Zhou.* Synthesis of Chiral SultamsviaPalladium-catalyzed Intramolecular Asymmetric Reductive Amination.Chem. Commun.2017,53, 1704-1707.

27. Wen-Xue Huang, Chang-Bin Yu, Yue Ji, Lian-Jin Liu and Yong-Gui Zhou.* Ir-Catalyzed Asymmetric Hydrogenation of Heteroaromatics Bearing a Hydroxyl Group, 3-Hydroxypyridinium Salts. ACS Catal20166, 2368-2371.

26. Zhang-Pei Chen, Mu-Wang Chen, Lei Shi, Chang-Bin Yu and Yong-Gui Zhou.* Pd-catalyzed Asymmetric Hydrogenation of Fluorinated Aromatic Pyrazol-5-ols via Capture of Active Tautomers. Chem. Sci. 20156, 3415-3419. 

25. Bo Song, Chang-Bin Yu, Wen-Xue Huang, Mu-Wang Chen and Yong-Gui Zhou.* Formal Palladium-Catalyzed Asymmetric Hydrogenolysis of Racemic N-Sulfonyloxaziridines. Org. Lett201517, 190-193.

24. Chang-Bin Yu, Wen-Xue Huang, Lei Shi, Mu-Wang Chen, Bo Wu and Yong-Gui Zhou.* Asymmetric Hydrogenationvia Capture of Active Intermediates Generated from Aza-Pinacol Rearrangement. J. Am. Chem. Soc. 2014, 136, 15837-15840.

23. Wen-Xue Huang, Chang-Bin Yu, Lei Shi and Yong-Gui Zhou.* Iridium-Catalyzed Asymmetric Hydrogenation of Pyrrolo[1,2-a]pyrazinium Salts. Org. Lett. 201416, 3324-3327.

22. Ying Duan, Lu Li, Mu-Wang Chen, Chang-Bin Yu, Hong-Jun Fan* and Yong-Gui Zhou.* Homogenous Pd-Catalyzed Asymmetric Hydrogenation of Unprotected Indoles: Scope and Mechanistic Studies. J. Am. Chem. Soc. 2014136, 7688-7700.

21. Bo Wu, Mu-Wang Chen, Zhi-Shi Ye, Chang-Bin Yu and Yong-Gui Zhou.* A Streamlined Synthesis of 2,3-Dihydrobenzofurans via the ortho-Quinone Methides Generated from 2-Alkyl-Substituted Phenols. Adv. Synth. Catal. 2014356, 383-387.

20.Chang-Bin Yu and Yong-Gui Zhou*. Palladium-Catalyzed Asymmetric Hydrogenolysis of N-Sulfonyl Aminoalcoholsvia Achiral Enesulfonamide Intermediates. Angew. Chem. Int. Ed. 201352, 13365-13368.

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19. Kai Gao, Bo Wu, Chang-Bin Yu, Qing-An Chen, Zhi-Shi Ye and Yong-Gui Zhou.* Iridium Catalyzed Asymmetric Hydrogenation of Cyclic Imines of Benzodiazepinones and Benzodiazepines. Org. Lett201214, 3890-3893.

                                                                                                                                                                                                                                                                                                                               

18.Chang-Bin Yu, Kai Gao, Qing-An Chen, Mu-Wang Chen and Yong-Gui Zhou.* Enantioselective Pd-Catalyzed Hydrogenation of Tetrasubstituted Olefins of Cyclicβ-(Arylsulfonamido)acrylates. Tetrahedron Lett. 201253, 2560-2563.

17. De-Yang Zhang,Chang-Bin Yu, Min-Can Wang,* Kai Gao and Yong-Gui Zhou.* A New Electronically Deficient Atropisomeric Diphosphine Ligand (S)-CF3OBiPhep and Its Application in Asymmetric Hydrogenation. Tetrahedron Lett. 201253, 2556-2559.

16. Kai Gao,Chang-Bin Yu, Duo-Sheng Wang and Yong-Gui Zhou.* Iridium-Catalyzed Asymmetric Hydrogenation of 3-Substituted 2H-1,4-Benzoxazines. Adv. Synth. Catal. 2012354, 483-488.

15. Ying Duan, Mu-Wang Chen, Qing-An Chen, Chang-Bin Yu and Yong-Gui Zhou.* Pd-Catalyzed Asymmetric Hydrogenation of 3-(Toluenesulfonamidoalkyl)indoles. Org. Biomol. Chem. 201210, 1235-1238.

14. Qing-An Chen, Mu-Wang Chen, Chang-Bin Yu, Lei Shi, Duo-Sheng Wang, Yan Yang and Yong-Gui Zhou.* Biomimetic Asymmetric Hydrogenation: In Situ Regenerable Hantzsch Esters for Asymmetric Hydrogenation of Benzoxazinones. J. Am. Chem. Soc. 2011133, 16432-16435.

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13. De-Yang Zhang, Duo-Sheng Wang, Min-Can Wang,* Chang-Bin Yu, Kai Gao and Yong-Gui Zhou.* Synthesis of Electronically Deficient Atropisomeric Bisphosphine Ligands and Their Application in Asymmetric Hydrogenation of Quinolines. Synthesis 2011, 2796-2802.

12. Kai Gao, Chang-Bin Yu, Wei Li, Yong-Gui Zhouand Xumu Zhang.* Synthesis and Enantioselective Hydrogenation of Seven-membered Cyclic Imines: Substituted Dibenzo[b,f][1,4]oxazepines. Chem. Commun. 2011, 7845-7847.

11. Duo-Sheng Wang, Zhi-Shi Ye, Qing-An Chen, Yong-Gui Zhou,* Chang-Bin Yu, Hong-Jun Fan* and Ying Duan. Highly Enantioselective Partial Hydrogenation of Simple Pyrroles: A Facile Access to Chiral 1-Pyrrolines. J. Am. Chem. Soc. 2011133, 8866-8869.

10. Chang-Bin Yu, Kao Gao, Duo-Sheng Wang, Lei Shi and Yong-Gui Zhou.* Enantioselective Pd-catalyzed Hydrogenation of Enesulfonamides. Chem. Commun. 201147,5052-5054.

       

9. Duo-Sheng Wang, Jie Tang, Yong-Gui Zhou,* Mu-Wang Chen, Chang-Bin Yu, Ying Duan and Guo-Fang Jiang.* Dehydration Triggered Asymmetric Hydrogenation of 3-(a-hydroxyalkyl)indoles. Chem. Sci. 2011, 2, 803-806.       

8. Mu-Wang Chen, Ying Duan, Qing-An Chen, Duo-Sheng Wang, Chang-Bin Yu and Yong-Gui Zhou.* Enantioselective Pd-Catalyzed Hydrogenation of Fluorinated Imines: Facile Access to Chiral Fluorinated Amines. Org. Lett201012, 5075-5077.        

7. Duo-Sheng Wang, Qing-An Chen, Wei Li, Chang-Bin Yu, Yong-Gui Zhou* and Xumu Zhang.* Pd-Catalyzed Asymmetric Hydrogenation of Unprotected Indoles Activated by Bronsted Acids. J. Am. Chem. Soc. 2010132, 8909-8911.       

6. Ben-Hu Zhu, Jun-Cheng Zheng, Chang-Bin Yu, Xiu-Li Sun, Yong-Gui Zhou, Qi Shen* and Yong Tang.* One-Pot Highly Diastereoselective Synthesis of cis-Vinylaziridinesviathe Sulfur Ylide-Mediated Aziridination and Palladium(0)-Catalyzed Isomerization. Org. Lett201012, 504.

5. Chang-Bin Yu, Da-Wei Wang and Yong-Gui Zhou.Highly Enantioselective Synthesis of Sultams via Pd-Catalyzed Hydrogenation. J. Org. Chem. 200974, 5633-5635.

4. Xiao-Bing Wang, Da-Wei Wang, Sheng-Mei Lu, Chang-Bin Yu and Yong-Gui Zhou.Highly Enantioselective Ir-catalyzed Hydrogenation of Exocyclic Enamines. Tetrahedron: Asymmetry 200920, 1040-1045.

3. Da-Wei Wang, Xiao-Bing Wang, Duo-Sheng Wang, Sheng-Mei Lu, Chang-Bin Yu and Yong-Gui Zhou.Highly Enantioselective Iridium-Catalyzed Hydrogenation of 2-Benzylquinolines, 2-Functionalized and 2,3-Disubstituted Quinolines. J. Org. Chem. 200974, 2780-2787.       

2. You-Qing Wang, Chang-Bin Yu, Da-Wei Wang, Xiao-Bing Wang and Yong-Gui Zhou.* Enantioselective Synthesis of Cyclic Sulfamidates via Pd Catalyzed Hydrogenation. Org. Lett. 200810, 2071-2074.       

1. Qi-Bin Liu, Chang-Bin Yu and Yong-Gui Zhou.* Synthesis of Tunable Phosphinite-pyridine Ligands and Their Application in Asymmetric Hydrogenation. Tetrahedron Lett200647, 4733-4736.