Pyridines-手性合成研究组

Pyridines

Publications List:

4. Wen-Xue Huang, Chang-Bin Yu, Yue Ji, Lian-Jin Liu and Yong-Gui Zhou.* Ir-Catalyzed Asymmetric Hydrogenation of Heteroaromatics Bearing a Hydroxyl Group, 3-Hydroxypyridinium Salts. ACS Catal. 2016, 6, 2368-2371.

3. Mu-Wang Chen, Zhi-Shi Ye, Zhang-Pei Chen, Bo Wu and Yong-Gui Zhou.* Enantioselective Synthesis of TrifluoromethylSubstituted Piperidines with Multiple StereogenicCenters via Hydrogenation of Pyridinium Hydrochlorides. Org. Chem. Front. 2015, 2, 586-589.

2. Zhi-Shi Ye, Mu-Wang Chen, Qing-An Chen, Lei Shi, Ying Duan and Yong-Gui Zhou.* Ir-Catalyzed Asymmetric Hydrogenation of Pyridinium Salts. Angew. Chem. Int. Ed. 2012, 51, 10181-10184.

1. Xiao-Bing Wang, Wei Zeng, and Yong-Gui Zhou.* Iridium-catalyzed Asymmetric Hydrogenation of Pyridine Derivatives 7,8-Dihydro-quinolin-5(6H)-ones. Tetrahedron Lett. 2008, 49, 4922-4924.

Other's Work:

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20. Bo Qu,* Hari P. R. Mangunuru, Sergei Tcyrulnikov, Daniel Rivalti, Olga V. Zatolochnaya, Dmitry Kurouski, Suttipol Radomkit, Soumik Biswas, Shuklendu Karyakarte, Keith R. Fandrick, Joshua D. Sieber, Sonia Rodriguez, Jean-Nicolas Desrosiers, Nizar Haddad, Keith McKellop, Scott Pennino, Heewon Lee, Nathan K. Yee, Jinhua J. Song, Marisa C. Kozlowski,* and Chris H. Senanayake. Enantioselective Synthesis of α‑(Hetero)aryl Piperidines through Asymmetric Hydrogenation of Pyridinium Salts and Its Mechanistic Insights. Org. Lett. 2018, 20, 1333-1337.

19. Xudong Wei,* Bo Qu,* Xingzhong Zeng et al. Sequential C−H Arylation and Enantioselective Hydro- genation Enables Ideal Asymmetric Entry to the Indenopiperidine Core of an 11β-HSD-1 Inhibitor. J. Am. Chem. Soc. 2016, 138, 15473-15481.

18. Bo Qu,* Hari P. R. Mangunuru, Xudong Wei et al. Synthesis of Enantioenriched 2-Alkyl Piperidine Derivatives through Asymmetric Reduction of Pyridinium Salts. Org. Lett. 2016, 18, 4920-4923.

17. Marc Renom-Carrasco, Piotr Gajewski, Luca Pignataro, Johannes G. de Vries, Umberto Piarulli, Cesare Gennari, and Laurent Lefort.* A Mixed Ligand Approach for the Asymmetric Hydrogenation of 2-Sub- stituted Pyridinium Salts. Adv. Synth. Catal. 2016, 358, 2589.

16. Atsuhiro Iimuro, Kosuke Higashida, Yusuke Kita and Kazushi Mashima.* Asymmetric Hydrogenation of 3-Amido-2-arylpyridinium Salts by Triply Chloride-Bridged Dinuclear Iridium Complexes Bearing Enan- tiopure Diphosphine Ligands: Synthesis of Neurokinin-1 Receptor Antagonist Derivatives. Adv. Synth. Catal. 2016, 358, 1929-1933.

15. Marc Renom-Carrasco, Piotr Gajewski, Luca Pignataro, Johannes G. de Vries, Umberto Piarulli, Cesare Gennari and Laurent Lefort.* Asymmetric Hydrogenation of 3-Substituted Pyridinium Salts. Chem. Eur. J. Org. 2016, 22, 9528-9532.

14. Alban Cadu, Puspesh K. Upadhya, and Pher G. Andersson.* Iridium-Catalyzed Asymmetric Hydroge- nation of Substituted Pyridines. Asian J. Org. Chem. 2013, 2, 1061-1065.

13. Mingxin Chang, Yuhua Huang, Shaodong Liu, Yonggang Chen,* Shane W. Krska, Ian W. Davies and Xumu Zhang.* Asymmetric Hydrogenation of Pyridinium Salts with an Iridium Phosphole Catalyst. Angew. Chem. Int. Ed. 2014, 53, 12761-12764.

12. Yusuke Kita, Atsuhiro Iimuro, Shoji Hida, and Kazushi Mashima.* Iridium-Catalzed Asymmetric Hydrogenation of Pyridinium Salts for Constructing Multiple Stereogenic Centers on Piperidines. Chem. Lett. 2014, 43, 284-286.

11. Vladimir Dragan, J.* Christopher McWilliams,* Ross Miller,* Karen Sutherland, John L. Dillon, and Michael K. O’Brien. Asymmetric Synthesis of Vabicaserin via Oxidative Multicomponent Annulation and Asymmetric Hydrogenation of a 3,4-Substituted Quinolinium Salt. Org. Lett. 2013, 15, 2942-2945.

10. Wei-Jun Tang, Jing Tan, Li-Jin Xu,* Kim-Hung Lam, Qing-Hua Fan, and Albert S. C. Chan. Highly Enantioselective Hydrogenation of Quinoline and Pyridine Derivatives with Iridium-(P-Phos) Catalyst. Adv. Synth. Catal. 2010, 352, 1055-1062.

9. Weijun Tang, Yawei Sun, Lijin Xu,* Tianli Wang, Qinghua Fan, Kim-Hung Lam and Albert S. C. Chan. Highly Efficient and Enantioselective Hydrogenation of Quinolines and Pyridines with Ir-Difluorphos Catalyst. Org. Biomol. Chem. 2010, 8, 3464-3471.

8. Claude Y. Legault, André B. Charette,* and Pier G. Cozzi. Iridium Catalyzed Enantioselective Hydroge- nation of N-iminopyridinium Ylides: Mechanistic Insights. Hetereocycles 2008, 76, 1271-1283.

7. Magnus Rueping* and Andrey P. Antonchick. Organocatalytic Enantioselective Reduction of Pyridines. Angew. Chem. Int. Ed. 2007, 46, 4562-4565.

6. Aiwen Lei,* Mao Chen, Minsheng He, and Xumu Zhang.* Asymmetric Hydrogenation of Pyridines: Enantioselective Synthesis of Nipecotic Acid Derivatives. Eur. J. Org. Chem. 2006, 4343-4347.

5. Claude Y. Legault and Andre B. Charette*. Catalytic Asymmetric Hydrogenation of N-Iminopyridinium Ylides: Expedient Approach to Enantioenriched Substituted Piperidine Derivatives. J. Am. Chem. Soc. 2005, 127, 8966-8967.

4. Frank Glorius,* Nick Spielkamp, Sigrid Holle, Richard Goddard, and Christian W. Lehmann. Efficient Asymmetric Hydrogenation of Pyridines. Angew. Chem. Int. Ed. 2004, 43, 2850-2852.

3. Stuart A. Raynor, John Meurig Thomas,* Robert Raja, Brian F. G. Johnson,* Robert G. Bell and Mike D. Mantle. A One-step, Enantioselective Reduction of Ethyl Nicotinate to Ethyl Nipecotinate Using a Constrained, Chiral, Heterogeneous Catalyst. Chem. Commun. 2000, 1925-1926.

2. Martin Studer,* Christina Wedemeyer-Exl, Felix Spindler, and Hans-Ulrich Blaser. Enantioselective Homogeneous Hydrogenation of Monosubstituted Pyridines and Furans. Monatsh. Chem. 2000, 131, 1335–1343.

1. H.-U. Blaser, H. Honig, M. Studer, C. Wedemeyer-Exl. Enantioselective Synthesis of Ethyl Nipecotinate Using Cinchona Modified Heterogeneous Catalysts. J. Mol. Catal. A: Chem. 1999, 139, 253–257.

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