201

吴波 副研究员



吴波(Bo Wu)

Associate Professor


Dalian Institute of Chemical Physics,
Chinese Academy of Sciences,
457 Zhongshan Road, Dalian 116023, P. R. China

Tel: 86-411-84379325 (office)
E-mail: bowu@dicp.ac.cn
http://www.researcherid.com/rid/R-9231-2017

 

Educational and Professional Background:

2016.11-2018.1, Post-doctoral researcher in the group of Prof. Karol S. Bruzik, University of Illinois at Chicago, USA.
2012.9-2016.7, Ph. D. in Organic Chemistry, Advisor Prof. Yong-Gui Zhou, Dalian Institute of Chemical Physics, CAS.
2011.9-2012.7, Graduate Course, University of Science and Technology of China.
2007.9-2011.7, B.S. in Chemistry, Hunan University.

 

Awards:

 
 
Representative Publications:

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36. Xin-Wei Wang, Xiang Li, Mu-Wang Chen, Bo Wu and Yong-Gui Zhou.* Chiral Phosphoric Acid-Catalyzed Pictet-Spengler Reactions for Synthesis of 5',11'-Dihydrospiro[indoline-3,6'-indolo[3,2‑c]- quinolin]-2-ones Containing Quaternary Stereocenters. J. Org. Chem. 2021, 86, 6897−6906.

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35. Wen-Jun Huang, Ya-Ya Ma, Li-Xia Liu, Bo Wu, Guo-Fang Jiang,* and Yong-Gui Zhou.* Chiral Phosphoric Acid-Catalyzed C6 Functionalization of 2,3-Disubstituted Indoles for Synthesis of Hetero-triarylmethanes. Org. Lett. 2021, 23, 2393-2398.

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34. Xin-Wei Wang, Mu-Wang Chen, Bo Wu, Baomin Wang, Boshun Wan, and Yong-Gui Zhou.* Chiral Phosphoric Acid-Catalyzed Regioselective Synthesis of Spiro Aminals with Quarternary Stereocenters. Tetrahedron Lett. 2021, 62, 152793.

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33. Zi-Biao Zhao, Xiang Li, Mu-Wang Chen, Bo Wu and Yong-Gui Zhou.Enantioselective Synthesis of Tetrahydroquinolines via One-pot Cascade Biomimetic Reduction. Chin. J. Chem. 2020, 38, 1691-1695.

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32. Zhou-Hao Zhu, Yi-Xuan Ding, Bo Wu and Yong-Gui Zhou.* Design and Synthesis of Chiral and Regenerable [2.2]Paracyclophane-Based NAD(P)H Models and Application in Biomimetic Reduction of Flavonoids. Chem. Sci. 2020, 11, 10220-10224.

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31. Huan-Ping Xie, Bo Wu, Mu-Wang Chen, Chang-Bin Yu, Hong-Wang Li, Xiang Li and Yong-Gui Zhou.* Enantioselective Synthesis of Triarylmethanes Bearing Pyrazole Moiety through Squaramide-catalyzed Addition of Azadienes with Pyrazolin-5-ones. Chin. J. Org. Chem. 2020, 34, 3452-3462.

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30. Xiao-Qing Wang, Xiao-Yong Zhai, Bo Wu, Yu-Qing Bai and Yong-Gui Zhou.* Synthesis of Chiral Poly(silyl ether)s via CuH-Catalyzed Hydrosilylation Polymerization of Diketones with Silanes. ACS Macro Lett. 2020, 9, 969-973.

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29. Xiang Li, Zi-Biao Zhao, Mu-Wang Chen, Bo Wu, Chang-Bin Yu* and Yong-Gui Zhou.* Palladium-catalyzed Asymmetric Hydrogenation of 2-Aryl Cyclic Ketones for the Synthesis of trans Cycloalkanols through Dynamic Kinetic Resolution under Acidic Conditions. Chem. Commun. 2020, 56, 5815-5818.

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28. Zi-Biao Zhao, Xiang Li, Bo Wu and Yong-Gui Zhou.* Biomimetic Asymmetric Reduction of Quinazolinones with Chiral and Regenerable NAD(P)H Models. Chin. J. Chem. 2020, 38, 714-718.

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27. Huan-Ping Xie, Lei Sun, Bo Wu and Yong-Gui Zhou.* Copper-Catalyzed Alkynylation/ Cyclization/ Isomerization Cascade for Synthesis of 1,2-Dihydrobenzofuro[3,2-b]pyridines and Benzofuro[3,2-b] pyridines. J. Org. Chem. 2019, 84, 15498-15507.

26. Yang Zhao, Han Wang, Bo Wu and Yong-Gui Zhou.* Synthesis of Paracyclophanes with Planar and Central Chirality: Kinetic Resolution of [2.2]paracyclophane Aldimines via Palladium-Catalyzed Addition of Arylboronic Acids. Org. Chem. Front. 2019, 6, 3956-3960.

25. Xin-Wei Wang, Mu-Wang Chen, Bo Wu, Baomin Wang and Yong-Gui Zhou.* Chiral Phosphoric Acid-Catalyzed Synthesis of Fluorinated 5,6-Dihydroindolo[1,2-c]quinazolines with Quaternary Stereocenters. J. Org. Chem. 2019, 84, 8300-8308.

24. Huan-Ping Xie, Bo Wu, Xin-Wei Wang and Yong-Gui Zhou.* Chiral Brønsted Acid-Catalyzed Conjugate Addition of Indoles to Azadienes: Enantioselective Synthesis of Hetero-Triarylmethanes. Chin. J. Catal. 2019, 40, 1566-1575.

23. Hong-Qiang Shen, Bo Wu, Huan-Ping Xie and Yong-Gui Zhou.* Preparation of Axially Chiral 2,2'-Biimidazole Ligands through Remote Chirality Delivery and Their Application in Asymmetric Carbene Insertion into N-H of Carbazoles. Org. Lett. 2019, 21, 2712-2717.

22. Zheng Gu, Bo Wu, Guo-Fang Jiang and Yong-Gui Zhou.* Synthesis of Benzofuran‐fused 1,4‐Dihydropyridines via Bifunctional Squaramide-catalyzed Formal [4+2] Cycloaddition of Azadienes with Malononitrile. Chin. J. Chem. 2018, 36, 1130-1134.

   

21. Huan-Ping Xie,  Zhong Yan, Bo Wu, Shu-Bo Hu  and Yong-Gui Zhou.* Synthesis of Electron-Deficient (Sa,R,R)-(CF3)2-C3-TunePhos and Its  Applications in Asymmetric Hydrogenation of α-Iminophosphonates. Tetrahedron Lett. 2018, 59, 2960-2964.

       
20. Bo Wu, Zhaoyuan Yu,  Xiang Gao,  Yu Lan* and Yong-Gui Zhou.* Regioselective α-Addition of Deconjugated Butenolides: Enantioselective Synthesis of Dihydrocoumarins. Angew. Chem. Int. Ed. 2017, 56, 4006-4010.

19. Mu-Wang Chen, Bo Wu,  Zhang-Pei Chen, Lei Shi and Yong-Gui Zhou.* Synthesis of Chiral Fluorinated Propargylamines via Chemoselective Biomimetic Hydrogenation. Org. Lett. 2016, 18, 4650-4653.

   

18. Xiang Gao, Bo Wu,  Zhong Yan and Yong-Gui Zhou.* Copper-catalyzed Enantioselective C–H Functionalization of Indoles with an Axially Chiral Bipyridine Ligand. Org. Biomol. Chem. 2016, 14, 8237-8240.

   

17. Zhong Yan, Bo Wu, Xiang Gao and Yong-Gui Zhou.* Enantioselective Synthesis of Quaternary α-aminophosphonates by Pd-catalyzed Arylation of Cyclic α-ketiminophosphonates with Arylboronic Acids. Chem. Commun. 2016, 52, 10882-10885.

   

16. Wen-Xue Huang, Lian-Jin Liu, Bo Wu, Guang-Shou Feng, Baomin Wang  and Yong-Gui Zhou.* Synthesis of Chiral Piperazines via Hydrogenation of Pyrazines Activated by Alkyl Halides. Org. Lett. 2016, 18, 3082–3085.

   

15. Zhong Yan,                                  Bo Wu, Xiang Gao, Mu-Wang Chen and Yong-Gui Zhou.* Enantioselective Synthesis of                                 α-Amino Phosphonates                                  via Pd-Catalyzed Asymmetric Hydrogenation.                                  Org. Lett.                                   2016,                                  18, 692-695.                                        

14.                                 Bo Wu, Xiang Gao, Zhong Yan, Mu-Wang Chen, and Yong-Gui Zhou.* C-H Oxidation/Michael Addition/Cyclization Cascade for Enantioselective  Synthesis of Functionalized 2-Amino-4                                 H-chromenes.                                   Org. Lett.                                 2015,                                    17, 6134-6137.                                          

13. Xiang Gao, Bo Wu, Zhong Yan, and Yong-Gui Zhou.* Enantioselective Palladium-catalyzed Arylation of N-tosylarylimines with Arylboronic Acids Using a Chiral 2,2’-bipyridine Ligand. Org. Biomol. Chem. 2016, 14, 55-58.

12. Xiang Gao, Bo Wu, Wen-Xue Huang, Mu-Wang Chen, and Yong-Gui Zhou.* Enantioselective Palladium-Catalyzed C-H Functionalization of Indoles Using an Axially Chiral 2,2’-Bipyridine Ligand. Angew. Chem. Int. Ed. 2015, 54, 11956-11960.

11. Bo Wu, Xiang Gao, Zhong Yan, Wen-Xue Huang, and Yong-Gui Zhou.* Enantioselective Synthesis of Functionalized 2-Amino-4H-chromenes via the o-Quinone Methides Generated from 2-(1-Tosylalkyl)phenols. Tetrahedron Lett. 2015, 56, 4334-4338.

10. Mu-Wang Chen, Zhi-Shi Ye, Zhang-Pei Chen, Bo Wu and Yong-Gui Zhou.* Enantioselective Synthesis of Trifluoromethyl Substituted Piperidines with Multiple Stereogenic Centers via hydrogenation of Pyridinium Hydrochlorides. Org. Chem. Front. 2015, 2, 586-589.

9. Wen-Xue Huang, Bo Wu, Xiang Gao, Mu-Wang Chen, Baomin Wang,* and Yong-Gui Zhou.* Iridium-Catalyzed Selective Hydrogenation of 3-Hydroxypyridinium Salts: A Facile Synthesis of Piperidin-3-ones. Org. Lett. 2015, 17, 1640-1643.

8. Wengang Guo, Bo Wu, Xin Zhou, Ping Chen, Xu Wang, Yong-Gui Zhou, Yan Liu,* and Can Li*  Formal Asymmetric Catalytic Thiolation with a Bifunctional Catalyst at a Water–Oil Interface: Synthesis of Benzyl Thiols. Angew. Chem. Int. Ed. 2015, 54, 4522-4526.


7. Bo Wu, Xiang Gao, Mu-Wang Chen and Yong-Gui Zhou.* Direct amination of 2-(1-tosylalkyl) phenols with aqueous ammonia: a metal-free synthesis of primary amines. Tetrahedron Lett. 2015, 56, 1135–1137.

6. Chang-Bin Yu, Wen-Xue Huang, Lei Shi, Mu-Wang Chen, Bo Wu, and Yong-Gui Zhou.* Asymmetric Hydrogenation via Capture of Active Intermediates Generated from Aza-Pinacol Rearrangement. J. Am. Chem. Soc. 2014, 136, 15837-15840.

5. Bo Wu, Xiang Gao, Mu-Wang Chen, and Yong-Gui Zhou.* A Concise Synthesis of 2-(2-Hydroxy-phenyl)acetonitriles via the o-Quinone Methides Generated from 2-(1-Tosylalkyl)phenols. Chin. J. Chem. 2014, 32, 981-984.

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4. Jing Luo, Bo Wu, Mu-Wang Chen, Guo-Fang Jiang* and Yong-Gui Zhou.* The Concise Synthesis of Spiro-Cyclopropane Compounds via the Dearomatization of Indole Derivatives. Org. Lett. 2014, 16, 2578-2581.

 

3. Xian-Feng Cai, Ran-Ning Guo, Guang-Shou Feng, Bo Wu and Yong-Gui Zhou.* Chiral Phosphoric Acid-Catalyzed Asymmetric Transfer Hydrogenation of Quinolin-3-amines. Org. Lett. 2014, 16, 2680-2683.

 

2. Bo Wu, Mu-Wang Chen, Zhi-Shi Ye, Chang-Bin Yu and Yong-Gui Zhou.* A Streamlined Synthesis of 2,3-Dihydrobenzofurans via the ortho-Quinone Methides Generated from 2-Alkyl-Substituted Phenols. Adv. Synth. Catal. 2014, 356, 383-387.

 

1. Kai Gao, Bo Wu, Chang-Bin Yu, Qing-An Chen, Zhi-Shi Ye and Yong-Gui Zhou.* Iridium Catalyzed Asymmetric Hydrogenation of Cyclic Imines of Benzodiazepinones and Benzodiazepines. Org. Lett. 2012, 14, 3890–3893.
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